MD Scientific

10. november 2021

Estimate antibody glycosylation patterns and their affinity for the Fc receptor

TSKgel FcR-IIIA

  • Separation of mAbs according to Fc receptor affinity
  • Analysis of supernatant or purified mAbs
  • Fast HPLC analysis (20-30 min)
  • Estimate mAb glycosylation
  • Estimate antibody-dependent cellular cytotoxicity activity (ADCC)

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Product used

TSKgel FcR-IIIA columns are based on a recombinant Fc gamma IIIa receptor which is immobilized as a ligand on polymer particles. They separate monoclonal antibodies according their affinity to the receptor and enable a fast analysis of biological activity as well as fractionation along with biological activity

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